QuickView for RCC2;jsessionid=96F0662CAA6F6637C4A32FF7D84E8831 (gene)

Gene Symbol:

RCC2 Homo sapiens

Full name:

regulator of chromosome condensation 2

Synonyms:

TD-60, protein RCC2, RCC1-like protein TD-60, telophase disk protein of 60 kDa

Genomic Location:

Chr 1: 17605866-17638807

Description:

The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer.

The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  TCANNTGAY_SREBP1_01 ,  RYTTCCTG_ETS2_B ,  TTCNRGNNNNTTC_HSF_Q6 ,  HP1SITEFACTOR_Q6 ,  TTAYRTAA_E4BP4_01 ,  AML1_01 ,  TEF1_Q6 ,  CCAWYNNGAAR_UNKNOWN ,  ACTACCT_MIR196A_MIR196B ,  CREBP1_01 ,  HIF1_Q5 ,  NKX25_02 ,  RNGTGGGC_UNKNOWN ,  GTGCCTT_MIR506 ,  HLF_01 ,  AML1_Q6 ,  GGCAGCT_MIR22 ,  E2F_Q2 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  DR4_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-196 ,  Predicted Gene Targets for miR-22 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-29

Cytogenetic Map:

1p36.13

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