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QuickView for RECQL (gene)


Gene Symbol:
RECQL Homo sapiens Homo sapiens
Full name:
RecQ like helicase
Synonyms:
RECQL1, RecQ1, ATP-dependent DNA helicase Q1, DNA helicase, RecQ-like type 1, DNA-dependent ATPase Q1, RecQ helicase-like, RecQ protein-like (DNA helicase Q1-like), recQ protein-like 1
Genomic Location:
Chr 12: 21513965-21545796
Description:
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere mai...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 12
12p12.1





GO Molecular Function

four-way junction helicase activity | 3'-5' DNA helicase activity | nucleic acid binding | ribonucleotide binding | ATP-dependent DNA helicase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | ATP-dependent 3'-5' DNA helicase activity | purine ribonucleoside triphosphate binding | annealing helicase activity | DNA helicase activity | protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | helicase activity | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

double-strand break repair | DNA strand renaturation | four-way junction helicase activity | cellular process | 3'-5' DNA helicase activity | DNA geometric change | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | ATP-dependent DNA helicase activity | response to stimulus | response to stress | cellular nitrogen compound metabolic process | DNA recombination | DNA repair | nitrogen compound metabolic process | double-strand break repair via homologous recombination | cellular response to DNA damage stimulus | cellular response to stress | DNA duplex unwinding | ATP-dependent 3'-5' DNA helicase activity | annealing helicase activity | DNA helicase activity | DNA metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | recombinational repair | organelle organization | DNA conformation change | heterocycle metabolic process | chromosome organization | cellular metabolic process | macromolecule metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | membrane