QuickView for RFC3;jsessionid=2564C291B3B6B851089968AE32FD024B (gene)

Gene Symbol:

RFC3 Homo sapiens

Full name:

replication factor C subunit 3

Synonyms:

RFC38, replication factor C subunit 3, A1 38 kDa subunit, RF-C 38 kDa subunit, RFC, 38 kD subunit, activator 1 38 kDa subunit, activator 1 subunit 3, replication factor C (activator 1) 3, 38kDa, replication factor C 38 kDa subunit

Genomic Location:

Chr 13: 33290206-33438695

Description:

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subuni...

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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

13q13.2

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