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QuickView for RHO (gene)


Gene Symbol:
RHO Homo sapiens Homo sapiens
Full name:
rhodopsin
Synonyms:
CSNBAD1, OPN2, RP4, rhodopsin, opsin 2, rod pigment, opsin-2
Genomic Location:
Chr 3: 130730172-130736877
Description:
The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. Defects in this gene are a cause of congenital stationary night blindness.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3q22.1


Transcripts Names
NM_000539
Protein Names
Q16414
Q2M249
P08100



GO Molecular Function

isoprenoid binding | retinoid binding | cation binding | transmembrane signaling receptor activity | lipid binding | vitamin binding | G-protein coupled receptor activity | 11-cis retinal binding | G-protein coupled photoreceptor activity | signaling receptor activity | ion binding | photoreceptor activity | protein binding | metal ion binding | small molecule binding | retinal binding

GO Biological Process

response to radiation | detection of stimulus | eye development | tissue homeostasis | detection of light stimulus | cellular process | anatomical structure homeostasis | regulation of cellular process | absorption of visible light | cellular lipid metabolic process | G-protein coupled receptor activity | response to stimulus | cellular response to light stimulus | multicellular organismal homeostasis | G-protein coupled receptor signaling pathway | protein modification process | macromolecule modification | phototransduction | detection of abiotic stimulus | response to light stimulus | retinoid metabolic process | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | G-protein coupled photoreceptor activity | phosphorus metabolic process | lipid metabolic process | nervous system process | cellular response to radiation | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | cell communication | homeostatic process | protein metabolic process | rhodopsin mediated signaling pathway | retina development in camera-type eye | anatomical structure development | metabolic process | visual perception | light absorption | organic substance metabolic process | animal organ development | sensory perception of light stimulus | retina homeostasis | diterpenoid metabolic process | photoreceptor cell maintenance | camera-type eye development | sensory perception | regulation of cell communication | signaling | cellular protein metabolic process | isoprenoid metabolic process | regulation of G-protein coupled receptor protein signaling pathway | regulation of rhodopsin mediated signaling pathway | developmental process | cellular protein modification process | detection of visible light | phototransduction, visible light | cellular metabolic process | protein-chromophore linkage | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

non-motile cilium | integral component of membrane | intracellular membrane-bounded organelle | neuron projection | ciliary membrane | organelle membrane | cell projection membrane | photoreceptor outer segment membrane | cytoplasmic vesicle | Golgi-associated vesicle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | cell-cell junction | Golgi apparatus | cell projection | endomembrane system | plasma membrane | Golgi-associated vesicle | cilium | photoreceptor inner segment | photoreceptor outer segment | vesicle | photoreceptor disc membrane | photoreceptor inner segment membrane | integral component of plasma membrane | 9+0 non-motile cilium | Golgi membrane | photoreceptor cell cilium | membrane-bounded organelle | organelle | cell periphery | intracellular vesicle | intracellular | cell junction | membrane | intrinsic component of plasma membrane