QuickView for RIOK3 (gene)

Gene Symbol:

RIOK3 Homo sapiens

Full name:

RIO kinase 3

Synonyms:

SUDD, serine/threonine-protein kinase RIO3, homolog of the Aspergillus nidulans sudD gene product, sudD (suppressor of bimD6, Aspergillus nidulans) homolog, sudD homolog, sudD suppressor of Aspergillus nidulans bimD6 homolog, sudD suppressor of bimD6 homolog, testicular secretory protein Li 47

Genomic Location:

Chr 18: 19286785-19317099

Description:

This gene was first identified by the similarity of its product to the Aspergillus nidulans SUDD protein. This gene is now recognized as a member of the right open reading frame (RIO) kinase gene family. This gene encodes a serine/threonine kinase that localizes to the cytoplasm and plays a role in the processing of the pre-40 S ribosomal subunit. ...

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This gene was first identified by the similarity of its product to the Aspergillus nidulans SUDD protein. This gene is now recognized as a member of the right open reading frame (RIO) kinase gene family. This gene encodes a serine/threonine kinase that localizes to the cytoplasm and plays a role in the processing of the pre-40 S ribosomal subunit. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFMUE1_Q6 ,  TAL1ALPHAE47_01 ,  ATGTCAC_MIR489 ,  NKX3A_01 ,  IRF1_Q6 ,  AGGAGTG_MIR483 ,  TAL1BETAE47_01 ,  TTGGAGA_MIR5155P_MIR519E ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  ATTCTTT_MIR186 ,  ACTACCT_MIR196A_MIR196B ,  TTGTTT_FOXO4_01 ,  TAL1BETAITF2_01 ,  TGACAGNY_MEIS1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-196

Cytogenetic Map:

18q11.2

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