QuickView for RIPK4 (gene)
- Gene Symbol:
- RIPK4
Homo sapiens - Full name:
- receptor interacting serine/threonine kinase 4
- Synonyms:
- ANKK2, ANKRD3, DIK, NKRD3, PKK, PPS2, RIP4, receptor-interacting serine/threonine-protein kinase 4, PKC-delta-interacting protein kinase, ankyrin repeat domain-containing protein 3, protein kinase C-associated kinase, serine/threonine-protein kinase ANKRD3
- Genomic Location:
- Chr 21: 42032598-42060318
- Description:
-
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
TGANTCA_AP1_C , TTANTCA_UNKNOWN , HOXA4_Q2 , AP1_Q6 , CREB_Q4 , WTGAAAT_UNKNOWN , CREBP1_Q2 , PAX4_02 , GTGACGY_E4F1_Q6 , CAGGTG_E12_Q6
- Cytogenetic Map:
-
21q22.3
GO Molecular Function
ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | cellular process | tissue development | regulation of cellular process | regulation of metabolic process | epithelium development | protein serine/threonine kinase activity | protein modification process | macromolecule modification | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | phosphorus metabolic process | regulation of gene expression | regulation of nitrogen compound metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of RNA metabolic process | positive regulation of molecular function | protein metabolic process | tissue morphogenesis | regulation of DNA-binding transcription factor activity | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | protein kinase activity | organic substance metabolic process | positive regulation of NF-kappaB transcription factor activity | regulation of transcription, DNA-templated | cellular protein metabolic process | anatomical structure morphogenesis | kinase activity | developmental process | cellular protein modification process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
cell | cytoplasm | intracellular | membrane
