QuickView for RNASE4 (gene)
- Gene Symbol:
- RNASE4
Homo sapiens - Full name:
- ribonuclease A family member 4
- Synonyms:
- RAB1, RNS4, ribonuclease 4, RNase 4, ribonuclease A B1, ribonuclease, RNase A family, 4
- Genomic Location:
- Chr 14: 20222212-20238598
- Description:
-
The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' e...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
14q11.2
GO Molecular Function
nuclease activity | nucleic acid binding | hydrolase activity | ribonuclease activity | catalytic activity | ribonuclease A activity | endoribonuclease activity, producing 3'-phosphomonoesters | hydrolase activity, acting on ester bonds | organic cyclic compound binding | endoribonuclease activity | endonuclease activity | heterocyclic compound binding
GO Biological Process
RNA metabolic process | mRNA cleavage | nuclease activity | cellular process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | mRNA metabolic process | ribonuclease activity | ribonuclease A activity | nitrogen compound metabolic process | endoribonuclease activity, producing 3'-phosphomonoesters | endoribonuclease activity | metabolic process | RNA phosphodiester bond hydrolysis, endonucleolytic | nucleobase-containing compound metabolic process | organic substance metabolic process | RNA phosphodiester bond hydrolysis | endonuclease activity | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process
