cation binding | catalytic activity | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | ion binding | protein binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | metal ion binding
negative regulation of type I interferon production | proteolysis | regulation of immune system process | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | regulation of defense response to virus | interspecies interaction between organisms | regulation of interferon-beta production | catabolic process | regulation of type I interferon production | programmed cell death | cellular protein catabolic process | proteasomal protein catabolic process | protein modification process | macromolecule modification | apoptotic process | nitrogen compound metabolic process | protein catabolic process | negative regulation of cytokine production | protein modification by small protein conjugation | ubiquitin protein ligase activity | viral process | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | protein ubiquitination | cellular macromolecule catabolic process | metabolic process | ubiquitin-protein transferase activity | organic substance metabolic process | cell death | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | cellular protein metabolic process | regulation of cytokine production | cellular protein modification process | regulation of defense response to virus by host | protein K48-linked ubiquitination | cellular metabolic process | modification-dependent protein catabolic process | macromolecule metabolic process
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular