Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for ROR2 (gene)


Gene Symbol:
ROR2 Homo sapiens Homo sapiens
Full name:
receptor tyrosine kinase like orphan receptor 2
Synonyms:
BDB, BDB1, NTRKR2, tyrosine-protein kinase transmembrane receptor ROR2, neurotrophic tyrosine kinase receptor-related 2
Genomic Location:
Chr 9: 93524705-93752265
Description:
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly t...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Danio rerio Gallus gallus Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 9
9q22.31





GO Molecular Function

kinase binding | transmembrane receptor protein tyrosine kinase activity | cation binding | protein kinase binding | coreceptor activity | transmembrane signaling receptor activity | enzyme binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway | carbohydrate derivative binding | catalytic activity | ATP binding | frizzled binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | mitogen-activated protein kinase kinase kinase binding | protein tyrosine kinase activity | protein binding | coreceptor activity involved in Wnt signaling pathway | transferase activity, transferring phosphorus-containing groups | G-protein coupled receptor binding | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | Wnt-protein binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of JUN kinase activity | regulation of ERK1 and ERK2 cascade | limb development | SMAD protein signal transduction | inner ear morphogenesis | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | macrophage migration | embryonic genitalia morphogenesis | cell motility | developmental process involved in reproduction | intracellular signal transduction | regulation of localization | regulation of programmed cell death | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | regulation of immune system process | astrocyte development | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | embryonic appendage morphogenesis | cell differentiation | bone mineralization | nervous system development | neurogenesis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | positive regulation of cellular component movement | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | localization | positive regulation of synaptic transmission | limb morphogenesis | negative regulation of signaling | reproductive system development | positive regulation of protein kinase activity | negative regulation of apoptotic process | response to growth factor | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | tissue development | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | gliogenesis | positive regulation of stress-activated MAPK cascade | positive regulation of cellular protein metabolic process | epithelium development | regulation of establishment of planar polarity | MAPK cascade | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | cartilage condensation | embryonic limb morphogenesis | JNK cascade | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway | regulation of cell proliferation | positive regulation of protein kinase C activity | reproduction | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | protein modification process | cartilage development | modulation of chemical synaptic transmission | Wnt signaling pathway, planar cell polarity pathway | positive regulation of synaptic transmission, glutamatergic | embryo development | macromolecule modification | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | stress-activated protein kinase signaling cascade | anterior/posterior pattern specification | leukocyte migration | positive regulation of macrophage differentiation | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | locomotion | response to BMP | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | Wnt signaling pathway | multicellular organism development | cell migration | regulation of synaptic transmission, glutamatergic | regulation of MAPK cascade | phosphorus metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | non-canonical Wnt signaling pathway | positive regulation of cell migration | stress-activated MAPK cascade | regulation of cellular protein metabolic process | glial cell differentiation | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | transmembrane receptor protein serine/threonine kinase signaling pathway | skeletal system morphogenesis | astrocyte differentiation | regulation of protein metabolic process | positive regulation of signal transduction | inner ear development | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | genitalia development | embryonic morphogenesis | protein tyrosine kinase activity | positive regulation of molecular function | embryonic organ morphogenesis | Wnt signaling pathway, calcium modulating pathway | protein metabolic process | regionalization | positive regulation of protein modification process | response to organic substance | regulation of hemopoiesis | coreceptor activity involved in Wnt signaling pathway | regulation of kinase activity | male sex differentiation | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of programmed cell death | embryonic organ development | ear development | male genitalia development | protein kinase activity | organic substance metabolic process | connective tissue development | animal organ development | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | regulation of Wnt signaling pathway | genitalia morphogenesis | regulation of phosphate metabolic process | biomineral tissue development | regulation of JNK cascade | positive regulation of MAPK cascade | positive regulation of canonical Wnt signaling pathway | smoothened signaling pathway | anatomical structure formation involved in morphogenesis | BMP signaling pathway | regulation of stress-activated MAPK cascade | regulation of cell communication | regulation of macrophage differentiation | negative regulation of signal transduction | signaling | somite development | regulation of transcription, DNA-templated | glial cell development | cell development | embryonic digit morphogenesis | positive regulation of phosphorylation | cellular protein metabolic process | anatomical structure morphogenesis | positive regulation of MAP kinase activity | reproductive structure development | regulation of developmental process | kinase activity | segmentation | developmental process | negative regulation of canonical Wnt signaling pathway | cell aggregation | cellular protein modification process | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | somitogenesis | positive regulation of JUN kinase activity | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | ossification | cellular response to BMP stimulus | skeletal system development | positive regulation of myeloid leukocyte differentiation | immune system process | positive regulation of Wnt signaling pathway | cellular metabolic process | cellular response to organic substance | regulation of cell death | sex differentiation | positive regulation of cell motility | negative regulation of cell death | ear morphogenesis | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

supramolecular fiber | integral component of membrane | dendrite | neuron projection | clathrin-coated endocytic vesicle membrane | endocytic vesicle membrane | clathrin-coated vesicle membrane | somatodendritic compartment | organelle membrane | clathrin-coated vesicle | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic component of membrane | microtubule | cytoplasm | clathrin-coated endocytic vesicle | intracellular organelle | receptor complex | dendritic tree | protein-containing complex | cell projection | plasma membrane | vesicle | microtubule cytoskeleton | integral component of plasma membrane | coated vesicle membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | axon | intracellular vesicle | cell surface | cytoskeleton | endocytic vesicle | intracellular | membrane | supramolecular complex | cytoplasmic vesicle membrane | intrinsic component of plasma membrane | coated vesicle