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QuickView for RRM1 (gene)

Gene Symbol:
RRM1 Homo sapiens Homo sapiens
Full name:
ribonucleotide reductase catalytic subunit M1
R1, RIR1, RR1, ribonucleoside-diphosphate reductase large subunit, ribonucleoside-diphosphate reductase subunit M1, ribonucleotide reductase M1 polypeptide, ribonucleotide reductase, R1 subunit
Genomic Location:
Chr 11: 4072500-4116682
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multi...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 11

GO Molecular Function

ribonucleotide binding | disordered domain specific binding | nucleotide binding | carbohydrate derivative binding | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | catalytic activity | protein domain specific binding | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

brain development | response to radiation | protein heterotetramerization | developmental process involved in reproduction | gonad development | eye development | nervous system development | cellular process | nucleotide metabolic process | reproductive system development | deoxyribonucleotide biosynthetic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | development of primary sexual characteristics | head development | response to stimulus | cellular nitrogen compound biosynthetic process | reproduction | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cellular component assembly | cellular biosynthetic process | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | nucleotide biosynthetic process | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | phosphorus metabolic process | protein complex oligomerization | cell cycle | organophosphate metabolic process | deoxyribonucleotide metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | cell proliferation | biosynthetic process | aromatic compound biosynthetic process | protein tetramerization | phosphate-containing compound metabolic process | sensory organ development | cell proliferation in forebrain | protein-containing complex assembly | development of primary male sexual characteristics | retina development in camera-type eye | male sex differentiation | DNA metabolic process | anatomical structure development | mitotic cell cycle | metabolic process | oxidation-reduction process | male gonad development | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | forebrain development | neural precursor cell proliferation | camera-type eye development | pyrimidine nucleobase metabolic process | protein heterooligomerization | cellular macromolecule biosynthetic process | reproductive structure development | developmental process | carbohydrate derivative metabolic process | heterocycle metabolic process | central nervous system development | cellular metabolic process | sex differentiation | oxidoreductase activity | DNA replication | response to ionizing radiation | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | somatodendritic compartment | cell body | cell | oxidoreductase complex | neuronal cell body | cytoplasm | intracellular organelle | protein-containing complex | cell projection | endomembrane system | nuclear envelope | membrane-bounded organelle | nucleus | organelle | ribonucleoside-diphosphate reductase complex | cytosol | intracellular