QuickView for RRM1 (gene)

Gene Symbol:

RRM1 Homo sapiens

Full name:

ribonucleotide reductase catalytic subunit M1

Synonyms:

R1, RIR1, RR1, ribonucleoside-diphosphate reductase large subunit, ribonucleoside-diphosphate reductase subunit M1, ribonucleotide reductase M1 polypeptide, ribonucleotide reductase, R1 subunit

Genomic Location:

Chr 11: 4072500-4116682

Description:

This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multi...

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This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ZIC1_01 ,  EFC_Q6 ,  SRF_Q6 ,  GTACTGT_MIR101 ,  CTTTGA_LEF1_Q2 ,  GCCATNTTG_YY1_Q6 ,  CREB_Q3 ,  LEF1_Q2 ,  CAGGTA_AREB6_01 ,  HNF4_Q6 ,  RRAGTTGT_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  PAX6_01 ,  RNGTGGGC_UNKNOWN ,  HMGIY_Q6 ,  CEBP_C ,  IK1_01 ,  SMAD_Q6 ,  SRF_C

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101

Cytogenetic Map:

11p15.4

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