QuickView for RXRA (gene)

Gene Symbol:

RXRA Homo sapiens

Full name:

retinoid X receptor alpha

Synonyms:

NR2B1, retinoic acid receptor RXR-alpha, nuclear receptor subfamily 2 group B member 1, retinoid X nuclear receptor alpha

Genomic Location:

Chr 9: 136358231-136472252

Description:

Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The p...

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Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTGCAC_MIR19A_MIR19B ,  TTGCACT_MIR130A_MIR301_MIR130B ,  ACTGTGA_MIR27A_MIR27B ,  TGCACTG_MIR148A_MIR152_MIR148B ,  TGCCTTA_MIR124A ,  GTGCCTT_MIR506

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

9q34.2

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