QuickView for RXRB (gene)
- Gene Symbol:
- RXRB
Homo sapiens - Full name:
- retinoid X receptor beta
- Synonyms:
- DAUDI6, H-2RIIBP, NR2B2, RCoR-1, retinoic acid receptor RXR-beta, MHC class I promoter binding protein, nuclear receptor subfamily 2 group B member 2
- Genomic Location:
- Chr 6: 33269343-33276410
- Description:
-
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elemen...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
6p21.32
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | retinoic acid receptor activity | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | nucleic acid binding | steroid hormone receptor activity | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | ion binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | zinc ion binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transition metal ion binding | 9-cis retinoic acid receptor activity | transcription coregulator activity | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | response to hormone | retinoic acid receptor activity | RNA polymerase II transcription factor activity, sequence-specific DNA binding | hormone-mediated signaling pathway | retinoic acid receptor signaling pathway | positive regulation of cellular biosynthetic process | cellular process | nuclear receptor activity | transcription factor activity, direct ligand regulated sequence-specific DNA binding | positive regulation of nitrogen compound metabolic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | nitrogen compound metabolic process | regulation of gene expression | response to lipid | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | cell communication | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | response to organic substance | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | cellular response to steroid hormone stimulus | 9-cis retinoic acid receptor activity | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | intracellular receptor signaling pathway | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | response to steroid hormone | signal transduction | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
