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QuickView for Rab1A (gene)


Gene Symbol:
RAB1A Homo sapiens Homo sapiens
Full name:
RAB1A, member RAS oncogene family
Synonyms:
RAB1, YPT1, ras-related protein Rab-1A, GTP binding protein Rab1a, RAB1, member RAS oncogene family, Rab GTPase YPT1 homolog, YPT1-related protein
Genomic Location:
Chr 2: 65167493-65210793
Description:
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode dif...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Canis lupus familiaris Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2p14





GO Molecular Function

guanyl ribonucleotide binding | ribonucleoside binding | cadherin binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | cell adhesion molecule binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding

GO Biological Process

cell morphogenesis | microtubule-based transport | cell motility | intracellular signal transduction | endothelial cell development | cell-substrate adhesion | macroautophagy | hormone secretion | defense response to other organism | establishment of localization | substrate adhesion-dependent cell spreading | cell differentiation | endothelial cell differentiation | defense response | membrane organization | vesicle cytoskeletal trafficking | intracellular transport | microtubule-based process | cellular process | cargo loading into COPII-coated vesicle | secretion | peptide hormone secretion | establishment of organelle localization | localization | regulation of ubiquitin-protein transferase activity | protein transport | pigment granule transport | macromolecule localization | endomembrane system organization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | tissue development | vesicle targeting, to, from or within Golgi | interspecies interaction between organisms | cytoskeleton-dependent intracellular transport | regulation of cellular process | regulation of metabolic process | catabolic process | organelle localization | positive regulation of ubiquitin protein ligase activity | small GTPase mediated signal transduction | interleukin-8 production | positive regulation of cellular protein metabolic process | epithelium development | cellular component organization | viral life cycle | response to stimulus | positive regulation of protein metabolic process | COPII-coated vesicle budding | response to stress | intracellular protein transport | organelle transport along microtubule | regulation of protein ubiquitination | epithelial cell development | microtubule-based movement | cellular localization | secretion by cell | cellular component assembly | protein modification process | melanosome localization | macromolecule modification | vesicle targeting | cell-cell signaling | locomotion | organelle assembly | response to external biotic stimulus | growth hormone secretion | nitrogen compound metabolic process | endothelium development | autophagosome organization | cell migration | retrograde vesicle-mediated transport, Golgi to ER | regulation of catalytic activity | regulation of hormone levels | localization within membrane | vesicle coating | organic substance transport | cell projection assembly | positive regulation of cellular metabolic process | establishment of endothelial barrier | regulation of nitrogen compound metabolic process | peptide transport | vesicle-mediated transport | pigmentation | Golgi vesicle budding | interleukin-8 secretion | establishment of vesicle localization | regulation of cellular protein metabolic process | cellular protein-containing complex assembly | cell morphogenesis involved in differentiation | vacuole organization | autophagy | response to bacterium | peptide secretion | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | defense response to bacterium | establishment of endothelial intestinal barrier | Golgi vesicle transport | viral process | establishment of melanosome localization | positive regulation of molecular function | cytokine production | protein-containing complex assembly | protein metabolic process | positive regulation of protein modification process | autophagosome assembly | Golgi organization | import into cell | anatomical structure development | cell projection organization | metabolic process | cytokine secretion | transport along microtubule | Rab protein signal transduction | cellular protein localization | virion assembly | amide transport | endocytosis | cell adhesion | hormone transport | organic substance metabolic process | cilium assembly | establishment of protein localization | vesicle organization | positive regulation of glycoprotein metabolic process | vesicle budding from membrane | cilium organization | ER to Golgi vesicle-mediated transport | signaling | cell development | protein localization | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule localization | response to biotic stimulus | developmental process | organelle organization | COPII vesicle coating | cellular pigmentation | cellular protein modification process | vesicle transport along microtubule | Ras protein signal transduction | signal release | epithelial cell differentiation | cargo loading into vesicle | positive regulation of ubiquitin-protein transferase activity | positive regulation of metabolic process | vesicle localization | cellular metabolic process | pigment granule localization | protein secretion | positive regulation of protein ubiquitination | response to other organism | signal transduction | post-translational protein modification | macromolecule metabolic process | multicellular organismal process | melanosome transport

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | transport vesicle membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | melanosome | Golgi apparatus | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | vesicle | transport vesicle | extracellular exosome | Golgi membrane | endosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | extracellular space | early endosome | cytosol | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane