QuickView for Rad52 (gene)

Gene Symbol:

RAD52 Homo sapiens

Full name:

RAD52 homolog, DNA repair protein

Synonyms:

DNA repair protein RAD52 homolog, recombination protein RAD52, rhabdomyosarcoma antigen MU-RMS-40.23

Genomic Location:

Chr 12: 891516-929124

Description:

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to ...

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The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCATTTG_MIR105 ,  ATAGGAA_MIR202 ,  ZIC2_01 ,  TGCACTT_MIR519C_MIR519B_MIR519A

Cytogenetic Map:

12p13.33

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