QuickView for Rapa (gene)
- Gene Symbol:
- TRERF1
Homo sapiens - Full name:
- transcriptional regulating factor 1
- Synonyms:
- BCAR2, HSA277276, RAPA, TREP132, TReP-132, dJ139D8.5, transcriptional-regulating factor 1, breast cancer anti-estrogen resistance 2, rapa-1, rapa-2, transcriptional regulating protein 132, zinc finger protein rapa, zinc finger transcription factor TReP-132
- Genomic Location:
- Chr 6: 42303842-42527761
- Description:
-
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NFAT_Q4_01 , TGGAAA_NFAT_Q4_01 , FOXO1_02 , OCT1_07 , RTAAACA_FREAC2_01 , OCT1_05 , SMTTTTGT_UNKNOWN , STAT4_01 , MAZR_01 , GATA1_01
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
6p21.1
GO Molecular Function
transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | DNA binding | ion binding | organic cyclic compound binding | transcription coactivator activity | DNA binding, bending | protein binding | DNA-binding transcription factor activity | transcription factor binding | nuclear receptor transcription coactivator activity | transcription coregulator activity | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | positive regulation of macromolecule biosynthetic process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | sterol metabolic process | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | cholesterol catabolic process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | steroid biosynthetic process | cellular nitrogen compound biosynthetic process | alcohol metabolic process | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | organic hydroxy compound metabolic process | nitrogen compound metabolic process | alcohol catabolic process | multicellular organism development | steroid catabolic process | lipid metabolic process | regulation of hormone levels | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | regulation of hormone metabolic process | aromatic compound biosynthetic process | lipid biosynthetic process | regulation of cellular metabolic process | homeostatic process | transcription coactivator activity | regulation of RNA metabolic process | DNA-binding transcription factor activity | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | cholesterol metabolic process | nuclear receptor transcription coactivator activity | nucleobase-containing compound metabolic process | lipid catabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | steroid metabolic process | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | positive regulation of gene expression | regulation of hormone biosynthetic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | transcription factor complex | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | histone deacetylase complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
