QuickView for RhD (gene)

Gene Symbol:

RHD Homo sapiens

Full name:

Rh blood group D antigen

Synonyms:

CD240D, DIIIc, RH, RH30, RHCED, RHDVA(TT), RHDel, RHPII, RHXIII, Rh4, RhDCw, RhII, RhK562-II, RhPI, blood group Rh(D) polypeptide, D antigen (DCS), RH polypeptide 2, Rh blood group C antigen, Rh blood group CE antigen, Rh blood group CcEe antigen, Rh blood group antigen Evans, Rh blood group, D anitgen, RhD antigen, RhD blood group antigen, RhD polypeptide, Rhesus blood group D antigen allele DIII type 7, Rhesus system D polypeptide, blood group antigen D, blood group protein RHD, rhesus D antigen, truncated Rh blood group D antigen, truncated RhD, truncated rhesus D, truncated rhesus blood group D antigen

Genomic Location:

Chr 1: 25471568-25529523

Description:

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the Rh...

View Full Description

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA3_01 ,  E2F1_Q4_01 ,  GATA_Q6 ,  GATA_C ,  GATAAGR_GATA_C ,  E2F1_Q4 ,  E2F_Q6 ,  E2F_Q4 ,  E2F_03 ,  E2F1DP1RB_01 ,  SMAD_Q6 ,  E2F_Q3 ,  E2F_Q3_01

View More

View Less

Cytogenetic Map:

1p36.11

search → result