QuickView for S1PR2 (gene)

Gene Symbol:

S1PR2 Homo sapiens

Full name:

sphingosine-1-phosphate receptor 2

Synonyms:

AGR16, DFNB68, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2, sphingosine 1-phosphate receptor 2, CTD-2369P2.2, S1P receptor 2, S1P receptor EDG5, S1P receptor Edg-5, deafness, autosomal recessive 68, endothelial differentiation G-protein coupled receptor 5, endothelial differentiation, sphingolipid G-protein-coupled receptor, 5, sphingosine 1-phosphate receptor Edg-5

Genomic Location:

Chr 19: 10193109-10202948

Description:

This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness.

This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  STAT4_01 ,  TGANTCA_AP1_C ,  GATA1_03 ,  RYTTCCTG_ETS2_B ,  ATF4_Q2 ,  NFKAPPAB_01 ,  GATAAGR_GATA_C ,  MAF_Q6 ,  GATA1_04 ,  NFKAPPAB65_01 ,  GGGAGGRR_MAZ_Q6 ,  GTGACGY_E4F1_Q6 ,  RP58_01 ,  CAGGTG_E12_Q6 ,  BACH2_01 ,  LMO2COM_02 ,  AP1_Q2_01 ,  E4F1_Q6 ,  E2F1_Q3_01 ,  MYB_Q6 ,  BACH1_01 ,  TTGTTT_FOXO4_01 ,  AAAYRNCTG_UNKNOWN ,  PAX_Q6 ,  CREL_01 ,  CTTTGT_LEF1_Q2 ,  NFKB_Q6_01 ,  NFKB_C ,  GGGNNTTTCC_NFKB_Q6_01

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Cytogenetic Map:

19p13.2

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