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QuickView for SACM1L (gene)


Gene Symbol:
SACM1L Homo sapiens Homo sapiens
Full name:
SAC1 like phosphatidylinositide phosphatase
Synonyms:
SAC1, phosphatidylinositide phosphatase SAC1, SAC1 suppressor of actin mutations 1 like, suppressor of actin 1, suppressor of actin mutations 1-like protein
Genomic Location:
Chr 3: 45705947-45761905
Description:
This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate. Deletion of this gene in mouse results in preimplantation lethality. Other stu...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3p21.31





GO Molecular Function

phosphatidylinositol bisphosphate phosphatase activity | phosphatidylinositol-4-phosphate phosphatase activity | phosphatase activity | hydrolase activity | phosphatidylinositol monophosphate phosphatase activity | catalytic activity | hydrolase activity, acting on ester bonds | phosphatidylinositol phosphate phosphatase activity | protein binding | phosphatidylinositol-3-phosphatase activity | phosphoric ester hydrolase activity | phosphatidylinositol phosphate 4-phosphatase activity

GO Biological Process

phosphatidylinositol bisphosphate phosphatase activity | phosphatidylinositol metabolic process | phosphatidylinositol-4-phosphate phosphatase activity | phospholipid metabolic process | cellular process | cellular lipid metabolic process | phosphatase activity | phosphatidylinositol monophosphate phosphatase activity | cellular biosynthetic process | phosphorus metabolic process | lipid metabolic process | organophosphate metabolic process | phospholipid biosynthetic process | biosynthetic process | lipid biosynthetic process | phosphatidylinositol phosphate phosphatase activity | phosphate-containing compound metabolic process | lipid modification | glycerolipid metabolic process | glycerophospholipid biosynthetic process | phosphatidylinositol dephosphorylation | phosphatidylinositol-3-phosphatase activity | metabolic process | organic substance metabolic process | phosphatidylinositol biosynthetic process | dephosphorylation | phosphatidylinositol phosphate 4-phosphatase activity | glycerophospholipid metabolic process | phospholipid dephosphorylation | cellular metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | integral component of endoplasmic reticulum membrane | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | intracellular organelle | intrinsic component of endoplasmic reticulum membrane | receptor complex | endoplasmic reticulum | Golgi apparatus | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | plasma membrane | integral component of plasma membrane | Golgi membrane | membrane-bounded organelle | organelle | cell periphery | ionotropic glutamate receptor complex | transmembrane transporter complex | cation channel complex | ion channel complex | intracellular | membrane | AMPA glutamate receptor complex | intrinsic component of plasma membrane