QuickView for SAMP (gene)

Gene Symbol:

XPNPEP1 Homo sapiens

Full name:

X-prolyl aminopeptidase 1

Synonyms:

APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1, xaa-Pro aminopeptidase 1, X-Pro aminopeptidase 1, X-prolyl aminopeptidase (aminopeptidase P) 1, soluble, X-prolyl aminopeptidase 1, soluble, aminoacylproline aminopeptidase, aminopeptidase P, cytosolic, cytosolic aminopeptidase P, soluble aminopeptidase P

Genomic Location:

Chr 10: 111614514-111673192

Description:

This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.

This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  ATF6_01 ,  PEA3_Q6 ,  XBP1_01 ,  HEB_Q6 ,  TGCAAAC_MIR452 ,  GTGACGY_E4F1_Q6 ,  ATF_01 ,  AP4_Q6 ,  CREB_02 ,  RNGTGGGC_UNKNOWN ,  CP2_02 ,  CAGCTG_AP4_Q5 ,  AP4_Q5 ,  ER_Q6 ,  HIF1_Q3

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-452

Cytogenetic Map:

10q25.1

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