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QuickView for SCG5 (gene)


Gene Symbol:
SCG5 Homo sapiens Homo sapiens
Full name:
secretogranin V
Synonyms:
7B2, P7B2, SGNE1, SgV, neuroendocrine protein 7B2, pituitary polypeptide, prohormone convertase chaperone, secretogranin-5, secretory granule endocrine protein I, secretory granule, neuroendocrine protein 1 (7B2 protein)
Genomic Location:
Chr 15: 30721252-30776590
Description:
This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 15
15q13.3


Transcripts Names
NM_003020
NM_001144757



GO Molecular Function

guanyl ribonucleotide binding | ribonucleoside binding | ribonucleotide binding | nucleotide binding | enzyme inhibitor activity | carbohydrate derivative binding | unfolded protein binding | molecular function regulator | anion binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | nucleoside binding | purine ribonucleotide binding | enzyme regulator activity | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding

GO Biological Process

proteolysis | regulation of localization | establishment of localization | protein processing | intracellular transport | cellular process | neuropeptide signaling pathway | localization | protein transport | macromolecule localization | establishment of localization in cell | regulation of cellular process | response to stimulus | enzyme inhibitor activity | intracellular protein transport | cellular localization | cellular nitrogen compound metabolic process | G-protein coupled receptor signaling pathway | molecular function regulator | nitrogen compound metabolic process | negative regulation of catalytic activity | regulation of catalytic activity | regulation of hormone levels | regulation of hormone secretion | organic substance transport | peptide transport | cellular amide metabolic process | protein maturation | cell communication | peptide metabolic process | protein metabolic process | metabolic process | cellular protein localization | amide transport | regulation of secretion | organic substance metabolic process | gene expression | establishment of protein localization | peptide hormone processing | regulation of cell communication | negative regulation of molecular function | signaling | protein localization | enzyme regulator activity | hormone metabolic process | cellular macromolecule localization | regulation of transport | cellular metabolic process | signal transduction | regulation of signaling | macromolecule metabolic process

GO Cellular Component

secretory granule | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | secretory vesicle | endomembrane system | vesicle | extracellular region | membrane-bounded organelle | organelle | intracellular vesicle | intracellular