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QuickView for SCN3B (gene)


Gene Symbol:
SCN3B Homo sapiens Homo sapiens
Full name:
sodium voltage-gated channel beta subunit 3
Synonyms:
ATFB16, BRGDA7, HSA243396, SCNB3, sodium channel subunit beta-3, sodium channel, voltage-gated, type III, beta subunit, voltage-gated sodium channel beta-3 subunit
Genomic Location:
Chr 11: 123005105-123030525
Description:
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactiv...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 11
11q24.1





GO Molecular Function

sodium channel inhibitor activity | voltage-gated ion channel activity | channel regulator activity | passive transmembrane transporter activity | sodium channel regulator activity | voltage-gated sodium channel activity | transmembrane transporter activity | ion gated channel activity | ion channel inhibitor activity | molecular function regulator | ion channel binding | channel inhibitor activity | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | protein binding | metal ion transmembrane transporter activity | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

positive regulation of heart contraction | heart process | positive regulation of blood circulation | actin filament-based process | regulation of sodium ion transmembrane transporter activity | protein localization to cell periphery | regulation of localization | sodium channel inhibitor activity | regulation of sodium ion transport | regulation of ventricular cardiac muscle cell membrane depolarization | establishment of localization | nervous system development | membrane depolarization during action potential | voltage-gated ion channel activity | cellular process | channel regulator activity | localization | passive transmembrane transporter activity | regulation of sodium ion transmembrane transport | metal ion transport | macromolecule localization | actin filament-based movement | atrial cardiac muscle cell action potential | regulation of cellular process | sodium channel regulator activity | membrane depolarization during cardiac muscle cell action potential | voltage-gated sodium channel activity | transmembrane transporter activity | heart contraction | ventricular cardiac muscle cell action potential | actin-mediated cell contraction | muscle contraction | ion gated channel activity | ion channel inhibitor activity | regulation of blood circulation | regulation of heart rate | cellular localization | blood circulation | cell-cell signaling | molecular function regulator | regulation of membrane potential | system development | channel inhibitor activity | multicellular organism development | ion transmembrane transport | SA node cell to atrial cardiac muscle cell communication | protein localization to plasma membrane | protein localization to membrane | nervous system process | sodium ion transport | cation transmembrane transporter activity | regulation of membrane depolarization | monovalent inorganic cation transport | cardiac muscle cell action potential involved in contraction | ion transmembrane transporter activity | SA node cell action potential | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | sensory perception of pain | cell-cell signaling involved in cardiac conduction | regulation of heart contraction | cell communication | regulation of atrial cardiac muscle cell membrane depolarization | cardiac muscle cell contraction | homeostatic process | positive regulation of transport | striated muscle contraction | cation transmembrane transport | positive regulation of heart rate | regulation of heart rate by cardiac conduction | atrial cardiac muscle cell to AV node cell communication | metal ion transmembrane transporter activity | anatomical structure development | cellular protein localization | cell communication involved in cardiac conduction | chemical homeostasis | membrane depolarization | sodium ion transmembrane transport | positive regulation of ion transport | positive regulation of sodium ion transport | SA node cell to atrial cardiac muscle cell signaling | ion homeostasis | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | regulation of ion transmembrane transport | sodium channel activity | cation channel activity | sensory perception | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | voltage-gated channel activity | cation transport | cellular macromolecule localization | channel activity | regulation of ion transport | developmental process | regulation of transport | cardiac muscle cell action potential | ion channel activity | ion transport | cardiac muscle contraction | substrate-specific channel activity | muscle system process | cardiac conduction | multicellular organismal process

GO Cellular Component

supramolecular fiber | integral component of membrane | voltage-gated sodium channel complex | sarcomere | cell | plasma membrane protein complex | intrinsic component of membrane | myofibril | cytoplasm | intracellular organelle | contractile fiber | protein-containing complex | plasma membrane | integral component of plasma membrane | organelle | I band | sodium channel complex | cell periphery | transmembrane transporter complex | cation channel complex | ion channel complex | Z disc | intracellular | membrane | supramolecular complex | intrinsic component of plasma membrane