QuickView for SEC14L2 (gene)

Gene Symbol:

SEC14L2 Homo sapiens

Full name:

SEC14 like lipid binding 2

Synonyms:

C22orf6, SPF, TAP, TAP1, SEC14-like protein 2, alpha-tocopherol-associated protein, squalene transfer protein, supernatant protein factor, tocopherol-associated protein 1

Genomic Location:

Chr 22: 29122933-29149828

Description:

This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants enc...

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This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT1_02 ,  YATTNATC_UNKNOWN ,  NFKAPPAB_01 ,  STAT1_03 ,  GGGAGGRR_MAZ_Q6 ,  STAT_Q6 ,  CTTTAAR_UNKNOWN ,  RGAGGAARY_PU1_Q6 ,  STAT1_01 ,  CTTTGT_LEF1_Q2 ,  NFKB_Q6 ,  NFKB_C ,  CCTNTMAGA_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125

Cytogenetic Map:

22q12.2

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