QuickView for SEMA3F;jsessionid=96F0662CAA6F6637C4A32FF7D84E8831 (gene)

Gene Symbol:

SEMA3F Homo sapiens

Full name:

semaphorin 3F

Synonyms:

SEMA-IV, SEMA4, SEMAK, semaphorin-3F, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F, semaphorin III/F, semaphorin IV

Genomic Location:

Chr 3: 50167852-50201512

Description:

This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine...

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This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  MYOD_Q6_01 ,  MYOD_01 ,  RYTTCCTG_ETS2_B ,  CACGTG_MYC_Q2 ,  CIZ_01 ,  ATCTTGC_MIR31 ,  TGACCTY_ERR1_Q2 ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  AAAGACA_MIR511 ,  RORA1_01 ,  AREB6_03 ,  NMYC_01 ,  SCGGAAGY_ELK1_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  IK2_01 ,  CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  MZF1_02 ,  TGACCTTG_SF1_Q6 ,  CCACACA_MIR147

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-200b

Cytogenetic Map:

3p21.31

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