QuickView for SENP1 (gene)

Gene Symbol:

SENP1 Homo sapiens

Full name:

SUMO1/sentrin specific peptidase 1

Synonyms:

SuPr-2, sentrin-specific protease 1, SUMO1/sentrin specific protease 1, sentrin/SUMO-specific protease SENP1

Genomic Location:

Chr 12: 46723024-46785908

Description:

This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript ...

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This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  EFC_Q6 ,  TTTTGAG_MIR373 ,  ZF5_01 ,  AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D ,  GGGACCA_MIR133A_MIR133B ,  CIZ_01 ,  TAGCTTT_MIR9 ,  CTTTGA_LEF1_Q2 ,  TGACCTY_ERR1_Q2 ,  ATAGGAA_MIR202 ,  GGGAGGRR_MAZ_Q6 ,  RYTGCNWTGGNR_UNKNOWN ,  CAGGTA_AREB6_01 ,  CACCAGC_MIR138 ,  SP1_Q4_01 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  ACCAAAG_MIR9 ,  GGGCGGR_SP1_Q6 ,  AREB6_01 ,  TGCTGAY_UNKNOWN ,  EVI1_06 ,  MTF1_Q4 ,  PAX5_01 ,  NRF2_01 ,  AAGCACT_MIR520F ,  RCGCANGCGY_NRF1_Q6 ,  SP1_Q6_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  AAACCAC_MIR140 ,  PAX4_03 ,  DR4_Q2 ,  CACTTTG_MIR520G_MIR520H ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-122a ,  Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-339 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-140 ,  Predicted Gene Targets for miR-188 ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-376c ,  Predicted Gene Targets for miR-384 ,  Predicted Gene Targets for miR-543

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Cytogenetic Map:

12q13.11

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