QuickView for SEPT12;jsessionid=65B70E0ED3ED2FB48011AF319616F2CC (gene)
- Gene Symbol:
- SEPT12
Homo sapiens - Full name:
- septin 12
- Synonyms:
- SPGF10, septin-12, testicular tissue protein Li 168
- Genomic Location:
- Chr 16: 4767675-4778348
- Description:
-
This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Danio rerio , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
16p13.3
GO Molecular Function
structural molecule activity | GDP binding | guanyl ribonucleotide binding | ribonucleoside binding | ribonucleotide binding | lipid binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | phospholipid binding | pyrophosphatase activity | catalytic activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | protein dimerization activity | GTP binding | protein-containing complex scaffold activity | hydrolase activity, acting on acid anhydrides | phosphatidylinositol binding | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding
GO Biological Process
mitotic cytokinesis | cell motility | cell differentiation | male gamete generation | cellular process | septin ring organization | localization | cytoskeleton-dependent cytokinesis | multicellular organismal reproductive process | gamete generation | cellular component organization | sperm motility | reproduction | cellular component assembly | septin cytoskeleton organization | locomotion | organelle assembly | reproductive process | cell cycle | cell projection assembly | cell division | cytokinesis | cellular protein-containing complex assembly | multicellular organism reproduction | protein-containing complex assembly | mitotic cell cycle | cell projection organization | cilium assembly | cytoskeleton organization | cilium organization | developmental process | organelle organization | spermatogenesis | sexual reproduction | septin ring assembly | multicellular organismal process
GO Cellular Component
septin cytoskeleton | sperm flagellum | cleavage furrow | intracellular membrane-bounded organelle | cell | cytoplasm | spindle | intracellular organelle | actin cytoskeleton | 9+2 motile cilium | motile cilium | protein-containing complex | cell projection | sperm annulus | plasma membrane | midbody | actomyosin | septin ring | cilium | perinuclear region of cytoplasm | microtubule cytoskeleton | cytoplasmic region | cell cortex | membrane-bounded organelle | nucleus | organelle | cell division site | cell periphery | septin filament array | septin complex | stress fiber | cytoskeleton | intracellular | actin filament bundle | membrane
