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QuickView for SERPINA5;jsessionid=5AF227365818A7BACC2E502D0A8408D7 (gene)


Gene Symbol:
SERPINA5 Homo sapiens Homo sapiens
Full name:
serpin family A member 5
Synonyms:
PAI-3, PAI3, PCI, PCI-B, PLANH3, PROCI, plasma serine protease inhibitor, acrosomal serine protease inhibitor, plasminogen activator inhibitor III, plasminogen activator inhibitor-3, protein C inhibitor, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
Genomic Location:
Chr 14: 94117564-94129205
Description:
The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr 14
14q32.13


Transcripts Names
NM_000624



GO Molecular Function

endopeptidase inhibitor activity | isoprenoid binding | retinoid binding | cation binding | carboxylic acid binding | enzyme binding | lipid binding | enzyme inhibitor activity | carbohydrate derivative binding | phospholipid binding | molecular function regulator | anion binding | phosphatidylcholine binding | ion binding | heparin binding | protein binding | acrosin binding | glycosaminoglycan binding | serine-type endopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | retinoic acid binding | protease binding | organic acid binding | small molecule binding

GO Biological Process

endopeptidase inhibitor activity | developmental process involved in reproduction | lipid transport | establishment of localization | negative regulation of cellular process | membrane fusion | male gamete generation | membrane organization | negative regulation of proteolysis | cellular process | localization | reproductive system development | multicellular organismal reproductive process | macromolecule localization | hemostasis | regulation of proteolysis | negative regulation of cellular metabolic process | gamete generation | regulation of cellular process | regulation of metabolic process | cellular component organization | response to stimulus | enzyme inhibitor activity | response to stress | reproduction | negative regulation of metabolic process | molecular function regulator | blood coagulation | system development | reproductive process | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | regulation of catalytic activity | negative regulation of peptidase activity | wound healing | organic substance transport | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | fertilization | seminal vesicle development | regulation of cellular metabolic process | regulation of protein metabolic process | coagulation | single fertilization | multicellular organism reproduction | gland development | response to wounding | plasma membrane fusion | anatomical structure development | lipid localization | fusion of sperm to egg plasma membrane involved in single fertilization | regulation of body fluid levels | animal organ development | negative regulation of cellular protein metabolic process | serine-type endopeptidase inhibitor activity | negative regulation of protein metabolic process | negative regulation of molecular function | peptidase inhibitor activity | enzyme regulator activity | regulation of endopeptidase activity | reproductive structure development | developmental process | spermatogenesis | negative regulation of hydrolase activity | sexual reproduction | negative regulation of endopeptidase activity | multicellular organismal process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | protein C inhibitor-coagulation factor XI complex | organelle membrane | protein C inhibitor-KLK3 complex | cytoplasmic vesicle | protein C inhibitor-TMPRSS7 complex | cell | protein C inhibitor-plasma kallikrein complex | protein C inhibitor-TMPRSS11E complex | external side of plasma membrane | cytoplasm | protease inhibitor complex | acrosomal vesicle | intracellular organelle | platelet alpha granule | secretory granule membrane | protein C inhibitor-thrombin complex | protein-containing complex | secretory vesicle | endomembrane system | plasma membrane | serine protease inhibitor complex | vesicle | extracellular exosome | protein C inhibitor-coagulation factor V complex | acrosomal membrane | extracellular region | platelet dense tubular network | membrane-bounded organelle | extracellular vesicle | organelle | protein C inhibitor-coagulation factor Xa complex | vesicle membrane | protein C inhibitor-PLAU complex | extracellular space | cell periphery | protein C inhibitor-PLAT complex | intracellular vesicle | cell surface | intracellular | membrane | cytoplasmic vesicle membrane