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QuickView for SERPINA6 (gene)


Gene Symbol:
SERPINA6 Homo sapiens Homo sapiens
Full name:
serpin family A member 6
Synonyms:
CBG, corticosteroid-binding globulin, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6, serpin A6, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6, transcortin
Genomic Location:
Chr 14: 93840338-93859441
Description:
This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 14
14q32.13


Transcripts Names
NM_001756
Protein Names
A8K456
P08185
Q7Z2Q9



GO Molecular Function

endopeptidase inhibitor activity | lipid binding | enzyme inhibitor activity | molecular function regulator | organic cyclic compound binding | serine-type endopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | steroid binding

GO Biological Process

endopeptidase inhibitor activity | negative regulation of cellular process | negative regulation of proteolysis | regulation of proteolysis | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | enzyme inhibitor activity | negative regulation of metabolic process | molecular function regulator | negative regulation of catalytic activity | regulation of peptidase activity | regulation of catalytic activity | lipid metabolic process | regulation of hormone levels | negative regulation of peptidase activity | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | regulation of cellular metabolic process | regulation of protein metabolic process | metabolic process | organic substance metabolic process | negative regulation of cellular protein metabolic process | serine-type endopeptidase inhibitor activity | negative regulation of protein metabolic process | steroid metabolic process | negative regulation of molecular function | glucocorticoid metabolic process | peptidase inhibitor activity | enzyme regulator activity | hormone metabolic process | regulation of endopeptidase activity | negative regulation of hydrolase activity | negative regulation of endopeptidase activity

GO Cellular Component

vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space