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QuickView for SGK3 (gene)


Gene Symbol:
SGK3 Homo sapiens Homo sapiens
Full name:
serum/glucocorticoid regulated kinase family member 3
Synonyms:
CISK, SGK2, SGKL, serine/threonine-protein kinase Sgk3, cytokine-independent survival kinase
Genomic Location:
Chr 8: 67787445-67936811
Description:
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have be...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Schizosaccharomyces pombe Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 8
8q13.1





GO Molecular Function

channel regulator activity | ribonucleotide binding | sodium channel regulator activity | lipid binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | phospholipid binding | chloride channel regulator activity | molecular function regulator | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | potassium channel regulator activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | calcium channel regulator activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | phosphatidylinositol binding | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of extrinsic apoptotic signaling pathway in absence of ligand | intracellular signal transduction | regulation of localization | regulation of programmed cell death | peptidyl-amino acid modification | establishment of localization | negative regulation of cellular process | cellular process | channel regulator activity | regulation of cell motility | localization | negative regulation of signaling | negative regulation of apoptotic process | negative regulation of apoptotic signaling pathway | regulation of cellular process | sodium channel regulator activity | regulation of apoptotic process | regulation of metabolic process | response to stimulus | regulation of cell proliferation | protein serine/threonine kinase activity | chloride channel regulator activity | protein modification process | macromolecule modification | molecular function regulator | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of signal transduction | phosphorus metabolic process | ion transmembrane transport | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | negative regulation of extrinsic apoptotic signaling pathway | phosphorylation | potassium channel regulator activity | regulation of apoptotic signaling pathway | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | regulation of locomotion | regulation of RNA metabolic process | calcium channel regulator activity | protein metabolic process | regulation of growth | regulation of DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | protein kinase activity | organic substance metabolic process | regulation of cell communication | negative regulation of signal transduction | transmembrane transport | signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | kinase activity | regulation of cell growth | peptidyl-serine phosphorylation | cellular protein modification process | ion transport | cellular metabolic process | regulation of cell death | negative regulation of cell death | regulation of cellular component organization | signal transduction | regulation of signaling | macromolecule metabolic process

GO Cellular Component

cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | recycling endosome | endomembrane system | vesicle | endosome | membrane-bounded organelle | organelle | early endosome | cytosol | intracellular vesicle | intracellular