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QuickView for SLC16A1 (gene)


Gene Symbol:
SLC16A1 Homo sapiens Homo sapiens
Full name:
solute carrier family 16 member 1
Synonyms:
HHF7, MCT, MCT1, MCT1D, monocarboxylate transporter 1, MCT 1, solute carrier family 16 (monocarboxylate transporter), member 1, solute carrier family 16 (monocarboxylic acid transporters), member 1, solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Genomic Location:
Chr 1: 113255992-113300498
Description:
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 1
1p13.2


Transcripts Names
NM_003051
NM_001166496



GO Molecular Function

organic anion transmembrane transporter activity | anion transmembrane transporter activity | transmembrane transporter activity | organic acid transmembrane transporter activity | symporter activity | lactate transmembrane transporter activity | active transmembrane transporter activity | transporter activity | identical protein binding | ion transmembrane transporter activity | organic cyclic compound binding | mevalonate transmembrane transporter activity | carboxylic acid transmembrane transporter activity | protein binding | protein homodimerization activity | protein dimerization activity | monocarboxylic acid transmembrane transporter activity | secondary active transmembrane transporter activity

GO Biological Process

response to extracellular stimulus | response to nutrient levels | cell motility | regulation of localization | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | microtubule cytoskeleton organization | glucose homeostasis | regulation of peptide hormone secretion | microtubule-based process | cellular process | monocarboxylic acid transport | localization | anion transport | microtubule organizing center organization | regulation of cellular process | transmembrane transporter activity | cellular component organization | regulation of peptide secretion | response to stimulus | monocarboxylic acid metabolic process | regulation of insulin secretion | organic acid transmembrane transporter activity | organic hydroxy compound transport | cellular response to organic cyclic compound | regulation of protein transport | regulation of peptide transport | mevalonate transport | carboxylic acid transmembrane transport | symporter activity | leukocyte migration | locomotion | plasma membrane lactate transport | cell migration | behavioral response to nutrient | lipid metabolic process | regulation of hormone levels | ion transmembrane transport | lactate transmembrane transporter activity | regulation of hormone secretion | organic substance transport | cell cycle | active transmembrane transporter activity | small molecule metabolic process | response to nutrient | organic acid transport | ion transmembrane transporter activity | pyruvate metabolic process | lactate transmembrane transport | organic anion transport | mevalonate transmembrane transporter activity | carboxylic acid transmembrane transporter activity | homeostatic process | carboxylic acid metabolic process | regulation of establishment of protein localization | response to organic substance | centrosome cycle | anion transmembrane transport | organic acid transmembrane transport | metabolic process | chemical homeostasis | regulation of secretion | behavior | organic substance metabolic process | monocarboxylic acid transmembrane transporter activity | regulation of protein secretion | cytoskeleton organization | secondary active transmembrane transporter activity | regulation of cell communication | transmembrane transport | response to organic cyclic compound | organic acid metabolic process | carboxylic acid transport | organelle organization | regulation of transport | lactate transport | ion transport | immune system process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | response to food | carbohydrate homeostasis | regulation of signaling

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | microtubule organizing center | cell | intrinsic component of membrane | intracellular organelle | centrosome | plasma membrane | vesicle | extracellular exosome | microtubule cytoskeleton | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | cytoskeleton | intracellular | cell junction | membrane | intrinsic component of plasma membrane