QuickView for SLC22A2 (gene)

Gene Symbol:

SLC22A2 Homo sapiens

Full name:

solute carrier family 22 member 2

Synonyms:

OCT2, solute carrier family 22 member 2, organic cation transporter 2, solute carrier family 22 (organic cation transporter), member 2

Genomic Location:

Chr 6: 160557780-160599949

Description:

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twel...

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Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NKX25_01 ,  TGANTCA_AP1_C ,  AAAGGGA_MIR204_MIR211 ,  TGTGTGA_MIR377 ,  WTGAAAT_UNKNOWN ,  AR_Q6 ,  CTCTGGA_MIR520A_MIR525 ,  TGTTTGY_HNF3_Q6 ,  TTGTTT_FOXO4_01 ,  GTCTACC_MIR379

Cytogenetic Map:

6q25.3

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