QuickView for SLC22A4;jsessionid=51032E1AB59FCEB1B70EF0634A4F05AF (gene)

Gene Symbol:

SLC22A4 Homo sapiens

Full name:

solute carrier family 22 member 4

Synonyms:

DFNB60, OCTN1, solute carrier family 22 member 4, ET transporter, deafness, autosomal recessive 60, ergothioneine transporter, integral membrane transport protein, organic cation/carnitine transporter 1, solute carrier family 22 (organic cation/ergothioneine transporter), member 4, solute carrier family 22 (organic cation/zwitterion transporter), member 4

Genomic Location:

Chr 5: 131658044-131707798

Description:

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane...

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Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Cytogenetic Map:

5q31.1

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