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QuickView for SLC22A4 (gene)


Gene Symbol:
SLC22A4 Homo sapiens Homo sapiens
Full name:
solute carrier family 22 member 4
Synonyms:
DFNB60, OCTN1, solute carrier family 22 member 4, ET transporter, deafness, autosomal recessive 60, ergothioneine transporter, integral membrane transport protein, organic cation/carnitine transporter 1, solute carrier family 22 (organic cation/ergothioneine transporter), member 4, solute carrier family 22 (organic cation/zwitterion transporter), member 4
Genomic Location:
Chr 5: 131658044-131707798
Description:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 5
5q31.1


Protein Names
Q9H015
O14546



GO Molecular Function

ammonium transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | carbohydrate derivative binding | symporter activity | protein domain specific binding | ATP binding | anion binding | adenyl nucleotide binding | cation transmembrane transporter activity | antiporter activity | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | cation:cation antiporter activity | ion binding | organic cation transmembrane transporter activity | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | secondary active transmembrane transporter activity | purine ribonucleotide binding | PDZ domain binding | adenyl ribonucleotide binding | drug binding | carnitine transmembrane transporter activity | heterocyclic compound binding | quaternary ammonium group transmembrane transporter activity | small molecule binding | secondary active organic cation transmembrane transporter activity

GO Biological Process

establishment of localization | organic cation transport | cellular process | secretion | ammonium transmembrane transporter activity | localization | metal ion transport | triglyceride metabolic process | anion transport | transmembrane transporter activity | cellular lipid metabolic process | symporter activity | lipid metabolic process | ion transmembrane transport | organic substance transport | sodium ion transport | cation transmembrane transporter activity | amino-acid betaine transport | monovalent inorganic cation transport | antiporter activity | active transmembrane transporter activity | ion transmembrane transporter activity | cation:cation antiporter activity | organic anion transport | organic cation transmembrane transporter activity | glycerolipid metabolic process | cation transmembrane transport | neutral lipid metabolic process | metabolic process | carnitine transport | regulation of body fluid levels | body fluid secretion | ammonium transmembrane transport | carnitine transmembrane transport | organic substance metabolic process | secondary active transmembrane transporter activity | transmembrane transport | cation transport | ammonium transport | quaternary ammonium group transport | carnitine transmembrane transporter activity | ion transport | cellular metabolic process | quaternary ammonium group transmembrane transporter activity | acylglycerol metabolic process | secondary active organic cation transmembrane transporter activity

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | apical plasma membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | apical part of cell | plasma membrane | mitochondrion | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane | intrinsic component of plasma membrane