QuickView for SLC25A4 (gene)

Gene Symbol:

SLC25A4 Homo sapiens

Full name:

solute carrier family 25 member 4

Synonyms:

AAC1, ANT, ANT 1, ANT1, MTDPS12, MTDPS12A, PEO2, PEO3, PEOA2, T1, ADP/ATP translocase 1, ADP,ATP carrier protein 1, ADP,ATP carrier protein, heart/skeletal muscle, adenine nucleotide translocator 1 (skeletal muscle), heart/skeletal muscle ATP/ADP translocator, solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4

Genomic Location:

Chr 4: 186301392-186305419

Description:

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. M...

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This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  SRF_01 ,  SRF_Q6 ,  TMTCGCGANR_UNKNOWN ,  RYCACNNRNNRNCAG_UNKNOWN ,  CTAWWWATA_RSRFC4_Q2 ,  TGACCTY_ERR1_Q2 ,  WHN_B ,  MEF2_02 ,  STAT_Q6 ,  HNF4_01 ,  TATAAA_TATA_01 ,  ALPHACP1_01 ,  ATACCTC_MIR202 ,  YY1_01 ,  SRF_Q4 ,  SCGGAAGY_ELK1_02 ,  WTTGKCTG_UNKNOWN ,  TATA_01 ,  SRF_Q5_01 ,  TBP_01 ,  SMAD_Q6 ,  PAX4_03 ,  SRF_C

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-140

Cytogenetic Map:

4q35.1

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