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QuickView for SLC25A5 (gene)


Gene Symbol:
SLC25A5 Homo sapiens Homo sapiens
Full name:
solute carrier family 25 member 5
Synonyms:
2F1, AAC2, ANT2, T2, T3, ADP/ATP translocase 2, ADP,ATP carrier protein, fibroblast isoform, adenine nucleotide translocator 2 (fibroblast), solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
Genomic Location:
Chr X: 118486433-118489320
Description:
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. S...
Orthologs:
Mus musculus Rattus norvegicus Saccharomyces cerevisiae Macaca mulatta Danio rerio Bos taurus Canis lupus familiaris Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr X
Xq24


Transcripts Names
NM_001152
Protein Names
O43350
P05141
Q6NVC0



GO Molecular Function

ATP:ADP antiporter activity | organic anion transmembrane transporter activity | anion transmembrane transporter activity | enzyme binding | nucleic acid binding | transmembrane transporter activity | ATP transmembrane transporter activity | anion:anion antiporter activity | adenine nucleotide transmembrane transporter activity | ubiquitin-like protein ligase binding | antiporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | organic cyclic compound binding | drug transmembrane transporter activity | protein binding | purine nucleotide transmembrane transporter activity | adenine transmembrane transporter activity | ubiquitin protein ligase binding | nucleobase transmembrane transporter activity | secondary active transmembrane transporter activity | ADP transmembrane transporter activity | purine nucleobase transmembrane transporter activity | heterocyclic compound binding | RNA binding

GO Biological Process

response to cytokine | purine nucleotide transport | regulation of localization | regulation of programmed cell death | ATP:ADP antiporter activity | nucleobase transport | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | negative regulation of cellular process | negative regulation of mitochondrion organization | response to drug | regulation of organelle organization | regulation of peptide hormone secretion | membrane organization | cellular process | localization | negative regulation of signaling | anion transport | negative regulation of apoptotic process | interspecies interaction between organisms | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | transmembrane transporter activity | purine ribonucleotide transport | cellular component organization | regulation of peptide secretion | response to stimulus | chromosome segregation | regulation of insulin secretion | regulation of cell proliferation | negative regulation of transport | regulation of protein transport | regulation of peptide transport | mitochondrion organization | ATP transmembrane transporter activity | anion:anion antiporter activity | adenine nucleotide transmembrane transporter activity | nucleotide transmembrane transport | regulation of signal transduction | regulation of hormone levels | ion transmembrane transport | regulation of hormone secretion | regulation of mitochondrial membrane permeability | organic substance transport | mitochondrial transport | antiporter activity | active transmembrane transporter activity | ion transmembrane transporter activity | ATP transport | cellular response to cytokine stimulus | organic anion transport | purine-containing compound transmembrane transport | regulation of apoptotic signaling pathway | regulation of mitochondrion organization | mitochondrial membrane organization | adenine nucleotide transport | drug transmembrane transporter activity | positive regulation of cell proliferation | viral process | purine nucleotide transmembrane transporter activity | adenine transmembrane transporter activity | regulation of establishment of protein localization | response to organic substance | anion transmembrane transport | nucleobase-containing compound transport | negative regulation of programmed cell death | regulation of secretion | regulation of protein secretion | nucleobase transmembrane transporter activity | purine nucleobase transmembrane transport | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | ADP transport | secondary active transmembrane transporter activity | drug transport | regulation of cell communication | regulation of membrane permeability | negative regulation of signal transduction | transmembrane transport | cellular response to leukemia inhibitory factor | adenine transport | drug transmembrane transport | organelle organization | ADP transmembrane transporter activity | regulation of transport | purine nucleobase transmembrane transporter activity | purine nucleobase transport | ion transport | cellular response to organic substance | regulation of protein localization | regulation of cell death | negative regulation of cell death | regulation of cellular component organization | carbohydrate derivative transport | regulation of signaling

GO Cellular Component

mitochondrial matrix | integral component of membrane | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | MMXD complex | cell | intrinsic component of membrane | mitochondrial nucleoid | cytoplasm | nucleoid | spindle | intracellular organelle | membrane microdomain | protein-containing complex | plasma membrane | membrane raft | microtubule cytoskeleton | mitochondrion | integral component of plasma membrane | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | cell periphery | membrane-enclosed lumen | mitochondrial membrane | cytoskeleton | intracellular | myelin sheath | membrane | intrinsic component of plasma membrane