QuickView for SLC2A4;jsessionid=87B0FB3C37361706AF7BA5CD089E511C (gene)

Gene Symbol:

SLC2A4 Homo sapiens

Full name:

solute carrier family 2 member 4

Synonyms:

GLUT4, solute carrier family 2, facilitated glucose transporter member 4, GLUT-4, glucose transporter type 4, insulin-responsive, insulin-responsive glucose transporter type 4, solute carrier family 2 (facilitated glucose transporter), member 4

Genomic Location:

Chr 17: 7125778-7132091

Description:

This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, th...

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This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  MAZR_01 ,  TGGNNNNNNKCCAR_UNKNOWN ,  VDR_Q3 ,  YTATTTTNR_MEF2_02 ,  AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D ,  LXR_DR4_Q3 ,  RSRFC4_Q2 ,  CAGCACT_MIR5123P ,  SREBP1_Q6 ,  CTAWWWATA_RSRFC4_Q2 ,  CTCNANGTGNY_UNKNOWN ,  TGACCTY_ERR1_Q2 ,  TAAWWATAG_RSRFC4_Q2 ,  MEF2_02 ,  TATAAA_TATA_01 ,  RGAANNTTC_HSF1_01 ,  GGGYGTGNY_UNKNOWN ,  NFY_Q6_01 ,  LFA1_Q6 ,  TGCGCANK_UNKNOWN ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  NF1_Q6 ,  YKACATTT_UNKNOWN ,  CTTTAAR_UNKNOWN ,  NF1_Q6_01 ,  FREAC2_01 ,  WWTAAGGC_UNKNOWN ,  MEF2_03 ,  TATA_01 ,  SRF_Q5_01 ,  TBP_01 ,  RCGCANGCGY_NRF1_Q6 ,  LXR_Q3 ,  CACBINDINGPROTEIN_Q6 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  TGACCTTG_SF1_Q6 ,  SRF_C ,  GGGTGGRR_PAX4_03 ,  SF1_Q6 ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-93

Cytogenetic Map:

17p13.1

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