QuickView for SLC37A4 (gene)

Gene Symbol:

SLC37A4 Homo sapiens

Full name:

solute carrier family 37 member 4

Synonyms:

G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d, PRO0685, TRG-19, TRG19, glucose-6-phosphate exchanger SLC37A4, glucose-5-phosphate transporter, glucose-6-phosphatase, transport (glucose) protein 3, glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1, glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2, glucose-6-phosphate translocase, microsomal glucose-6-phosphate transporter, solute carrier family 37 (glucose-6-phosphate transporter), member 4, transformation-related gene 19 protein

Genomic Location:

Chr 11: 118400274-118406800

Description:

This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Al...

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This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  TTANTCA_UNKNOWN ,  HOXA4_Q2 ,  HNF1_C ,  AML1_01 ,  TATAAA_TATA_01 ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  ATACCTC_MIR202 ,  LHX3_01 ,  EVI1_02 ,  NKX62_Q2 ,  AP2_Q6_01 ,  EVI1_05 ,  PITX2_Q2 ,  HIF1_Q5 ,  YCATTAA_UNKNOWN ,  AML1_Q6 ,  CHX10_01 ,  TAATTA_CHX10_01 ,  MYOGENIN_Q6 ,  WTTGKCTG_UNKNOWN ,  HIF1_Q3 ,  COREBINDINGFACTOR_Q6 ,  GGGTGGRR_PAX4_03

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Cytogenetic Map:

11q23.3

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