QuickView for SLC4A4 (gene)

Gene Symbol:

SLC4A4 Homo sapiens

Full name:

solute carrier family 4 member 4

Synonyms:

HNBC1, KNBC, NBC1, NBC2, NBCe1-A, SLC4A5, hhNMC, kNBC1, pNBC, electrogenic sodium bicarbonate cotransporter 1, Na(+)/HCO3(-) cotransporter, sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney; sodium bicarbonate cotransporter, pancreas), solute carrier family 4 (sodium bicarbonate cotransporter), member 4, solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type, solute carrier family 4, sodium bicarbonate cotransporter, member 5

Genomic Location:

Chr 4: 72271867-72656663

Description:

This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene.

This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF1_01 ,  P53_DECAMER_Q2 ,  FOXO4_01 ,  TTTTGAG_MIR373 ,  CTACTGT_MIR199A ,  CTATGCA_MIR153 ,  GTGACTT_MIR224 ,  EVI1_04 ,  AACTGGA_MIR145 ,  VDR_Q6 ,  TACTTGA_MIR26A_MIR26B ,  AMEF2_Q6 ,  ACTTTAT_MIR1425P ,  CTTTGA_LEF1_Q2 ,  TAATGTG_MIR323 ,  TTGGAGA_MIR5155P_MIR519E ,  PAX4_02 ,  CATTTCA_MIR203 ,  CTCAGGG_MIR125B_MIR125A ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  GTCTTCC_MIR7 ,  NKX25_02 ,  CAGCAGG_MIR370 ,  OCT1_06 ,  AATGTGA_MIR23A_MIR23B ,  TTGTTT_FOXO4_01 ,  AFP1_Q6 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  HNF1_Q6

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-204 ,  Predicted Gene Targets for miR-214 ,  Predicted Gene Targets for miR-221 ,  Predicted Gene Targets for miR-224 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-338 ,  Predicted Gene Targets for miR-370 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-431 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-7 ,  Predicted Gene Targets for miR-149 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-375

View More

View Less

Cytogenetic Map:

4q13.3

search → result