QuickView for SLC4A7 (gene)

Gene Symbol:

SLC4A7 Homo sapiens

Full name:

solute carrier family 4 member 7

Synonyms:

NBC2, NBC3, NBCN1, SBC2, SLC4A6, sodium bicarbonate cotransporter 3, bicarbonate transporter, electroneutral Na/HCO(3) cotransporter, sodium bicarbonate cotransporter 2, sodium bicarbonate cotransporter 2b, solute carrier family 4, sodium bicarbonate cotransporter, member 7

Genomic Location:

Chr 3: 27389218-27473249

Description:

This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alt...

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This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  TACTTGA_MIR26A_MIR26B ,  GTGCAAA_MIR507 ,  GGATTA_PITX2_Q2 ,  TGCCTTA_MIR124A ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  NFY_Q6 ,  AGGTGCA_MIR500 ,  RORA1_01 ,  GFI1_01 ,  TTGCCAA_MIR182 ,  TTGTTT_FOXO4_01 ,  WTTGKCTG_UNKNOWN ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  RORA2_01 ,  ER_Q6_02 ,  ER_Q6_01 ,  AACTTT_UNKNOWN ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  ER_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-7 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-363 ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-486 ,  Predicted Gene Targets for miR-500

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Cytogenetic Map:

3p24.1

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