QuickView for SLC4A8 (gene)

Gene Symbol:

SLC4A8 Homo sapiens

Full name:

solute carrier family 4 member 8

Synonyms:

NBC3, NDCBE, electroneutral sodium bicarbonate exchanger 1, electroneutral Na(+)-driven Cl-HCO3 exchanger, k-NBC3, solute carrier family 4, sodium bicarbonate cotransporter, member 8

Genomic Location:

Chr 12: 50104861-50189247

Description:

The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding diff...

View Full Description

The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCANCTGNY_MYOD_Q6 ,  CAGGTG_E12_Q6

Cytogenetic Map:

12q13.13

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