QuickView for SLC6A1 (gene)

Gene Symbol:

SLC6A1 Homo sapiens

Full name:

solute carrier family 6 member 1

Synonyms:

GABATHG, GABATR, GAT1, MAE, sodium- and chloride-dependent GABA transporter 1, GABA transporter 1, solute carrier family 6 (neurotransmitter transporter), member 1, solute carrier family 6 (neurotransmitter transporter, GABA), member 1

Genomic Location:

Chr 3: 11009453-11055935

Description:

The protein encoded by this gene is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.

The protein encoded by this gene is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGTG_MIR128A_MIR128B ,  GTATTAT_MIR3693P ,  GAGCCTG_MIR484 ,  TTTNNANAGCYR_UNKNOWN ,  GCCATNTTG_YY1_Q6 ,  ACTGTGA_MIR27A_MIR27B ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  HIF1_Q5 ,  TGTTTGY_HNF3_Q6 ,  GACTGTT_MIR212_MIR132 ,  TCTATGA_MIR376A_MIR376B ,  TTGTTT_FOXO4_01 ,  AAAYRNCTG_UNKNOWN ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  HIF1_Q3 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-376 ,  Predicted Gene Targets for miR-496

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Cytogenetic Map:

3p25.3

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