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QuickView for SLCO1B3 (gene)


Gene Symbol:
SLCO1B3 Homo sapiens Homo sapiens
Full name:
solute carrier organic anion transporter family member 1B3
Synonyms:
HBLRR, LST-2, LST-3TM13, LST3, OATP-8, OATP1B3, OATP8, SLC21A8, solute carrier organic anion transporter family member 1B3, liver-specific organic anion transporter 2, liver-specific organic anion transporter 3TM13, organic anion transporter 8, organic anion transporter LST-3c, organic anion-transporting polypeptide 8, solute carrier family 21 (organic anion transporter), member 8
Genomic Location:
Chr 12: 20854905-20960925
Description:
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alt...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Bos taurus Gallus gallus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 12
12p12.2


Transcripts Names
NM_019844
NM_001349920
Protein Names
B3KP78
Q9NPD5



GO Molecular Function

bile acid transmembrane transporter activity | organic anion transmembrane transporter activity | anion transmembrane transporter activity | transmembrane transporter activity | organic acid transmembrane transporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | carboxylic acid transmembrane transporter activity | monocarboxylic acid transmembrane transporter activity | secondary active transmembrane transporter activity | lipid transporter activity | sodium-independent organic anion transmembrane transporter activity

GO Biological Process

bile acid transmembrane transporter activity | lipid transport | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | monocarboxylic acid transport | localization | anion transport | macromolecule localization | transmembrane transporter activity | organic acid transmembrane transporter activity | organic hydroxy compound transport | carboxylic acid transmembrane transport | ion transmembrane transport | organic substance transport | active transmembrane transporter activity | organic acid transport | ion transmembrane transporter activity | organic anion transport | carboxylic acid transmembrane transporter activity | sodium-independent organic anion transport | anion transmembrane transport | organic acid transmembrane transport | lipid localization | bile acid and bile salt transport | monocarboxylic acid transmembrane transporter activity | secondary active transmembrane transporter activity | transmembrane transport | carboxylic acid transport | lipid transporter activity | ion transport | sodium-independent organic anion transmembrane transporter activity

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | basolateral plasma membrane | membrane | intrinsic component of plasma membrane