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QuickView for SMPD3;jsessionid=4F3E745D2C96C6B4BDABA79C73C35308 (gene)


Gene Symbol:
SMPD3 Homo sapiens Homo sapiens
Full name:
sphingomyelin phosphodiesterase 3
Synonyms:
NSMASE2, sphingomyelin phosphodiesterase 3, nSMase-2, neutral sphingomyelinase 2, neutral sphingomyelinase II
Genomic Location:
Chr 16: 66949731-67039905
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 16
16q22.1





GO Molecular Function

cation binding | phospholipase activity | hydrolase activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | lipase activity | protein binding | sphingomyelin phosphodiesterase activity | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | metal ion binding

GO Biological Process

positive regulation of exosomal secretion | regulation of localization | hormone secretion | establishment of localization | cell differentiation | organophosphate catabolic process | positive regulation of sphingolipid biosynthetic process | phospholipid metabolic process | positive regulation of cellular biosynthetic process | cellular process | secretion | peptide hormone secretion | organic substance catabolic process | localization | immune system development | sphingolipid metabolic process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | cellular lipid metabolic process | regulation of ceramide biosynthetic process | positive regulation of lipid biosynthetic process | hematopoietic progenitor cell differentiation | secretion by cell | cellular nitrogen compound metabolic process | hemopoiesis | cell-cell signaling | positive regulation of exocytosis | system development | nitrogen compound metabolic process | regulation of exosomal secretion | multicellular organism development | phosphorus metabolic process | lipid metabolic process | regulation of hormone levels | positive regulation of secretion | organic substance transport | cell cycle | organophosphate metabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | peptide transport | cellular amide metabolic process | phospholipid catabolic process | membrane lipid catabolic process | phosphate-containing compound metabolic process | peptide secretion | cell communication | regulation of cellular metabolic process | sphingomyelin catabolic process | cellular lipid catabolic process | sphingomyelin metabolic process | positive regulation of transport | regulation of lipid biosynthetic process | positive regulation of ceramide biosynthetic process | regulation of exocytosis | anatomical structure development | metabolic process | membrane lipid metabolic process | amide transport | regulation of vesicle-mediated transport | regulation of secretion | hormone transport | lipid catabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | animal organ development | regulation of sphingolipid biosynthetic process | organonitrogen compound catabolic process | signaling | developmental process | regulation of transport | signal release | sphingolipid catabolic process | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | multicellular organismal process

GO Cellular Component

Golgi stack | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | Golgi cis cisterna | Golgi apparatus | Golgi cisterna | endomembrane system | plasma membrane | Golgi membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane