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QuickView for SNCB;jsessionid=FAC6F26501ACC752D755F6B36741828C (gene)


Gene Symbol:
SNCB Homo sapiens Homo sapiens
Full name:
synuclein beta
Synonyms:
beta-synuclein
Genomic Location:
Chr 5: 175979816-175990163
Description:
This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 5
5q35.2





GO Molecular Function

cation binding | enzyme inhibitor activity | molecular function regulator | lipase inhibitor activity | ion binding | cuprous ion binding | copper ion binding | transition metal ion binding | calcium ion binding | phospholipase inhibitor activity | enzyme regulator activity | metal ion binding

GO Biological Process

catechol-containing compound metabolic process | regulation of programmed cell death | negative regulation of neuron death | negative regulation of cellular process | response to metal ion | phenol-containing compound metabolic process | regulation of neuron death | cellular process | chemical synaptic transmission | negative regulation of apoptotic process | response to inorganic substance | regulation of cellular process | regulation of apoptotic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | enzyme inhibitor activity | cell-cell signaling | dopamine metabolic process | molecular function regulator | organic hydroxy compound metabolic process | negative regulation of neuron apoptotic process | nitrogen compound metabolic process | negative regulation of catalytic activity | regulation of catalytic activity | synaptic signaling | lipase inhibitor activity | synapse organization | cell communication | regulation of neuron apoptotic process | drug metabolic process | catecholamine metabolic process | metabolic process | negative regulation of programmed cell death | organic substance metabolic process | phospholipase inhibitor activity | negative regulation of molecular function | signaling | enzyme regulator activity | cellular metabolic process | regulation of cell death | negative regulation of cell death

GO Cellular Component

synapse | cell | cytoplasm | inclusion body | cytosol | intracellular