QuickView for SNX4;jsessionid=E3140089D06F67708964EBBFAC0287D0 (gene)

Gene Symbol:

SNX4 Homo sapiens

Full name:

sorting nexin 4

Synonyms:

ATG24B, sorting nexin-4

Genomic Location:

Chr 3: 126648184-126721748

Description:

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and...

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This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGCCTTA_MIR124A ,  TTGCCAA_MIR182 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  AAGCACA_MIR218

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-10 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-338 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-31

Cytogenetic Map:

3q21.2

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