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QuickView for SOCS6 (gene)


Gene Symbol:
SOCS6 Homo sapiens Homo sapiens
Full name:
suppressor of cytokine signaling 6
Synonyms:
CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4, suppressor of cytokine signaling 6, STAT induced STAT inhibitor-4, cytokine-inducible SH2 protein 4, suppressor of cytokine signaling 4
Genomic Location:
Chr 18: 66107117-66148414
Description:
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine sign...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 18
18q22.2





GO Molecular Function

kinase regulator activity | molecular function regulator | 1-phosphatidylinositol-3-kinase regulator activity | phosphatidylinositol 3-kinase regulator activity | protein binding | enzyme regulator activity

GO Biological Process

negative regulation of leukocyte activation | negative regulation of immune system process | intracellular signal transduction | proteolysis | phosphatidylinositol metabolic process | regulation of immune system process | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | JAK-STAT cascade | defense response | phospholipid metabolic process | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | kinase regulator activity | regulation of cellular process | regulation of metabolic process | catabolic process | cellular lipid metabolic process | response to stimulus | negative regulation of cell adhesion | response to stress | negative regulation of lymphocyte activation | cellular protein catabolic process | proteasomal protein catabolic process | protein modification process | regulation of cell adhesion | regulation of phosphatidylinositol 3-kinase activity | macromolecule modification | molecular function regulator | nitrogen compound metabolic process | phosphorus metabolic process | regulation of catalytic activity | lipid metabolic process | regulation of phosphorylation | 1-phosphatidylinositol-3-kinase regulator activity | phosphatidylinositol 3-kinase regulator activity | regulation of T cell activation | protein catabolic process | organophosphate metabolic process | regulation of lymphocyte activation | protein modification by small protein conjugation | negative regulation of T cell activation | phosphorylation | phosphate-containing compound metabolic process | lipid phosphorylation | regulation of lipid kinase activity | negative regulation of cell-cell adhesion | cell communication | regulation of cellular metabolic process | negative regulation of cell activation | lipid modification | glycerolipid metabolic process | regulation of phospholipid metabolic process | protein metabolic process | regulation of growth | protein ubiquitination | regulation of kinase activity | cellular macromolecule catabolic process | metabolic process | organic substance metabolic process | regulation of cell activation | protein modification by small protein conjugation or removal | regulation of phosphate metabolic process | organonitrogen compound catabolic process | signaling | cellular protein metabolic process | enzyme regulator activity | phosphatidylinositol phosphorylation | glycerophospholipid metabolic process | cellular protein modification process | regulation of cell-cell adhesion | regulation of lipid metabolic process | cellular metabolic process | signal transduction | post-translational protein modification | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

catalytic complex | phosphatidylinositol 3-kinase complex | immunological synapse | extrinsic component of membrane | cell | cytoplasm | protein-containing complex | plasma membrane | transferase complex | cell periphery | cytosol | intracellular | membrane