QuickView for SPINK1;jsessionid=DBD61CA45A8F05E6B5DA177159229349 (gene)

Gene Symbol:

SPINK1 Homo sapiens

Full name:

serine peptidase inhibitor, Kazal type 1

Synonyms:

PCTT, PSTI, Spink3, TATI, TCP, serine protease inhibitor Kazal-type 1, pancreatic secretory trypsin inhibitor, serine protease inhibitor, Kazal type 1, tumor-associated trypsin inhibitor

Genomic Location:

Chr 5: 147184339-147191453

Description:

The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical ...

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The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF1_C ,  HNF1_Q6 ,  HNF6_Q6

Cytogenetic Map:

5q32

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