QuickView for SPTBN1;jsessionid=CB04978FB0DC8B5BD46DEB87AC215E6B (gene)

Gene Symbol:

SPTBN1 Homo sapiens

Full name:

spectrin beta, non-erythrocytic 1

Synonyms:

ELF, HEL102, SPTB2, betaSpII, spectrin beta chain, non-erythrocytic 1, beta-G spectrin, beta-II spectrin, beta-fodrin, beta-spectrin 2, beta-spectrin II, beta-spectrin non-erythrocytic 1, embryonic liver beta-fodrin, epididymis luminal protein 102, fodrin beta chain, spectrin beta chain, brain 1, spectrin, non-erythroid beta chain 1

Genomic Location:

Chr 2: 54536958-54752087

Description:

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a famil...

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Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  PR_02 ,  AREB6_02 ,  AR_02 ,  SOX9_B1 ,  AP4_Q6 ,  AR_01 ,  CAGCTG_AP4_Q5 ,  ACCATTT_MIR522

Cytogenetic Map:

2p16.2

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