QuickView for SPTSSA (gene)

Gene Symbol:

SPTSSA Homo sapiens

Full name:

serine palmitoyltransferase small subunit A

Synonyms:

C14orf147, SSSPTA, serine palmitoyltransferase small subunit A, small subunit of serine palmitoyltransferase A

Genomic Location:

Chr 14: 33971895-34001219

Description:

Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [...

View Full Description

Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTGCAC_MIR19A_MIR19B ,  GCATTTG_MIR105 ,  ZF5_01 ,  ATCTTGC_MIR31 ,  CTTTGTA_MIR524 ,  CATTTCA_MIR203 ,  CAGCTTT_MIR320 ,  ACCAAAG_MIR9 ,  NFY_01 ,  GACTGTT_MIR212_MIR132 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  YWATTWNNRGCT_UNKNOWN

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-496

Cytogenetic Map:

14q13.1

search → result