QuickView for SRI;jsessionid=92271347B9F0B06840E10B1EA524794E (gene)

Gene Symbol:

SRI Homo sapiens

Full name:

sorcin

Synonyms:

CP-22, CP22, SCN, V19, sorcin, 22 kDa protein, H_RG167B05.1, calcium binding protein amplified in mutlidrug-resistant cells

Genomic Location:

Chr 7: 87672368-87694244

Description:

This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transc...

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This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACTTTAT_MIR1425P

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-542-3p

Cytogenetic Map:

7q21.12

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