QuickView for ST6GAL1 (gene)

Gene Symbol:

ST6GAL1 Homo sapiens

Full name:

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Synonyms:

SIAT1, ST6GalI, ST6N, beta-galactoside alpha-2,6-sialyltransferase 1, B-cell antigen CD75, CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, ST6 beta-galactosamide alpha-2,6-sialyltranferase 1, ST6Gal I, alpha 2,6-ST 1, sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase)

Genomic Location:

Chr 3: 188131210-188279035

Description:

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of ...

View Full Description

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACGTG_MYC_Q2 ,  CTCAGGG_MIR125B_MIR125A ,  USF_C ,  NMYC_01 ,  TTGTTT_FOXO4_01 ,  CTTTGT_LEF1_Q2 ,  PAX2_02 ,  HIF1_Q3 ,  ACACTGG_MIR199A_MIR199B

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-199

Cytogenetic Map:

3q27.3

search → result